MAIN KEGG FILE RESULTS

	WEB-based GEne SeT AnaLysis Toolkit

	*Translating gene lists into biological insights...*

User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

This table lists the enriched KEGG pathways, number of Entrez IDs in your user data set for the pathway, the corresponding Entrez IDs, and the statistics for the enriched pathway.
The statistic column lists:

C: the number of reference genes in the category
O: the number of genes in the gene set and also in the category
E: the expected number in the category
R: ratio of enrichment
rawP: p value from hypergeometric test
adjP: p value adjusted by the multiple test adjustment

Finally, the pathway name is linked to KEGG where the user ids are highlighted, the number of user gene ids is linked to a table with information about the user ids, and the Entrez IDs are linked to Entrez Gene.

PathwayName	#Gene	EntrezGene	Statistics
MAPK signaling pathway	13	2318 4215 627 836 1647 1850 6722 22808 6885 7042 22800 5495 2260	C=268;O=13;E=1.73;R=7.53;rawP=2.56e-08;adjP=6.40e-07
Regulation of actin cytoskeleton	12	10398 3682 54434 5500 22808 55740 88 22800 10627 1073 26230 2260	C=213;O=12;E=1.37;R=8.74;rawP=1.71e-08;adjP=6.40e-07
Tight junction	8	5515 10398 22808 88 9223 22800 10627 5516	C=132;O=8;E=0.85;R=9.40;rawP=2.49e-06;adjP=4.15e-05
Oocyte meiosis	5	5500 5515 10971 25847 5516	C=112;O=5;E=0.72;R=6.93;rawP=0.0008;adjP=0.0100
Cell cycle	5	10971 7465 1647 25847 7042	C=124;O=5;E=0.80;R=6.26;rawP=0.0013;adjP=0.0117
Neurotrophin signaling pathway	5	10971 4215 627 6272 5781	C=127;O=5;E=0.82;R=6.11;rawP=0.0014;adjP=0.0117
Toxoplasmosis	5	3717 836 6885 7042 2775	C=132;O=5;E=0.85;R=5.88;rawP=0.0017;adjP=0.0121
Focal adhesion	6	5500 2318 10398 88 858 10627	C=200;O=6;E=1.29;R=4.65;rawP=0.0020;adjP=0.0125
Amoebiasis	4	836 88 7042 7879	C=106;O=4;E=0.68;R=5.85;rawP=0.0050;adjP=0.0227
Protein processing in endoplasmic reticulum	5	22872 57134 23645 7415 9451	C=165;O=5;E=1.06;R=4.70;rawP=0.0045;adjP=0.0227

WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).